{"id":797722,"date":"2026-06-11T20:36:57","date_gmt":"2026-06-11T12:36:57","guid":{"rendered":"https:\/\/www.alphaseek.cn\/?p=797722"},"modified":"2026-06-11T20:36:57","modified_gmt":"2026-06-11T12:36:57","slug":"silence-therapeutics%e5%85%ac%e5%b8%83divesiran%e9%9a%8f%e8%ae%bf%e6%95%b0%e6%8d%ae%ef%bc%8c%e5%b1%95%e7%8e%b0%e6%8c%81%e4%b9%85%e7%96%97%e6%95%88%e5%92%8c%e5%90%8c%e7%b1%bb%e6%9c%80%e4%bd%b3%e6%bd%9c","status":"publish","type":"post","link":"https:\/\/www.alphaseek.cn\/?p=797722","title":{"rendered":"Silence Therapeutics\u516c\u5e03divesiran\u968f\u8bbf\u6570\u636e\uff0c\u5c55\u73b0\u6301\u4e45\u7597\u6548\u548c\u540c\u7c7b\u6700\u4f73\u6f5c\u529b"},"content":{"rendered":"<p>Silence Therapeutics\u672c\u5468\u57282026\u5e74<a href=\"https:\/\/www.alphaseek.cn\/?tag=%e6%ac%a7%e6%b4%b2\" title=\"View all posts in \u6b27\u6d32\" target=\"_blank\" class=\"tag_link\">\u6b27\u6d32<\/a>\u8840\u6db2\u5b66\u534f\u4f1a\u5e74\u4f1a\u4e0a\u516c\u5e03\u4e86\u5176\u5728\u7814siRNA\u7597\u6cd5divesiran\u76841\u671fSANRECO\u7814\u7a76\u6700\u65b0\u968f\u8bbf\u6570\u636e\u3002\u6570\u636e\u663e\u793a\uff0c\u8be5\u836f\u7269\u5728\u771f\u6027\u7ea2\u7ec6\u80de\u589e\u591a\u75c7\u60a3\u8005\u4e2d\u8868\u73b0\u51fa\u6301\u4e45\u7684\u7597\u6548\uff0c\u505c\u836f\u540e\u4ecd\u53ef\u7ef4\u6301\u5bf9\u7ea2\u7ec6\u80de\u538b\u79ef\u7684\u63a7\u5236\uff0c\u5e76\u663e\u8457\u6539\u5584\u75be\u75c5\u76f8\u5173\u75c7\u72b6\u548c\u751f\u6d3b\u8d28\u91cf\u3002<\/p>\n<p>\u8fd9\u98791\u671f\u7814\u7a76\u5171\u7eb3\u516521\u540d\u4f9d\u8d56\u653e\u8840\u6cbb\u7597\u7684\u771f\u6027\u7ea2\u7ec6\u80de\u589e\u591a\u75c7\u60a3\u8005\u3002\u5728\u6cbb\u7597\u524d\u7684\u516d\u4e2a\u6708\u5185\uff0c\u8fd9\u4e9b\u60a3\u8005\u5171\u63a5\u53d7\u4e8680\u6b21\u653e\u8840\u3002\u800c\u5728\u4e3a\u671f34\u5468\u7684\u79ef\u6781\u6cbb\u7597\u671f\u95f4\uff0c\u4ec5\u9700\u8fdb\u884c5\u6b21\u653e\u8840\uff0c\u4e14\u5747\u53d1\u751f\u5728\u57fa\u7ebf\u7ea2\u7ec6\u80de\u538b\u79ef\u6c34\u5e73\u9ad8\u4e8e45%\u7684\u60a3\u8005\u4e2d\u3002\u66f4\u503c\u5f97\u5173\u6ce8\u7684\u662f\uff0c\u5728\u672b\u6b21\u7ed9\u836f\u540e\u768416\u5468\u968f\u8bbf\u671f\u5185\uff0c\u4ec5\u8bb0\u5f55\u4e864\u6b21\u653e\u8840\u3002\u572814\u540d\u62e5\u6709\u66f4\u957f\u968f\u8bbf\u6570\u636e\u7684\u60a3\u8005\u4e2d\uff0c\u9996\u6b21\u653e\u8840\u7684\u4e2d\u4f4d\u65f6\u95f4\u957f\u8fbe287\u5929\u3002<\/p>\n<p>\u9664\u4e86\u653e\u8840\u9700\u6c42\u7684\u663e\u8457\u51cf\u5c11\uff0c\u5927\u591a\u6570\u60a3\u8005\u7684MPN-10\u603b\u75c7\u72b6\u8bc4\u5206\u4ece\u57fa\u7ebf\u81f3\u7b2c34\u5468\u5747\u6709\u6539\u5584\uff0c\u8868\u660e\u75be\u75c5\u76f8\u5173\u75c7\u72b6\u548c\u6574\u4f53\u751f\u6d3b\u8d28\u91cf\u5f97\u5230\u63d0\u5347\u3002\u5b89\u5168\u6027\u65b9\u9762\uff0cdivesiran\u8010\u53d7\u6027\u826f\u597d\uff0c\u672a\u89c2\u5bdf\u5230\u5242\u91cf\u9650\u5236\u6027\u6bd2\u6027\uff0c\u6700\u5e38\u89c1\u7684\u6cbb\u7597\u671f\u95f4\u4e0d\u826f\u4e8b\u4ef6\u4e3a\u8f7b\u5ea6\u4e14\u77ed\u6682\u7684\u6ce8\u5c04\u90e8\u4f4d\u53cd\u5e94\uff0c\u672a\u62a5\u544a\u4e0e\u6cbb\u7597\u76f8\u5173\u7684\u4e25\u91cd\u4e0d\u826f\u4e8b\u4ef6\u6216\u56e0\u6b64\u505c\u836f\u7684\u60c5\u51b5\u3002<\/p>\n<p>Silence Therapeutics\u9996\u5e2d\u533b\u5b66\u5b98Curtis Rambaran\u535a\u58eb\u8868\u793a\uff0c\u57281\u671f\u7814\u7a76\u4e2d\u89c2\u5bdf\u5230\u6301\u7eed\u7684\u7ea2\u7ec6\u80de\u538b\u79ef\u63a7\u5236\u3001\u75c7\u72b6\u6539\u5584\u4ee5\u53ca\u653e\u8840\u8d1f\u62c5\u7684\u663e\u8457\u4e14\u6301\u4e45\u7684\u51cf\u5c11\uff0c\u8fd9\u4e9b\u53d1\u73b0\u8fdb\u4e00\u6b65\u652f\u6301\u4e86\u4f4e\u9891\u7ed9\u836f\u7684\u6f5c\u529b\u3002\u76ee\u524d\u6b63\u5728\u8fdb\u884c\u76842\u671fSANRECO\u7814\u7a76\u6b63\u5728\u8bc4\u4f30\u6bcf\u516d\u5468\u548c\u6bcf\u5341\u4e8c\u5468\u4e24\u79cd\u7ed9\u836f\u65b9\u6848\uff0c\u5171\u7eb3\u516548\u540d\u4f9d\u8d56\u653e\u8840\u6cbb\u7597\u7684\u60a3\u8005\uff0c\u9876\u7ebf\u6570\u636e\u9884\u8ba1\u5c06\u4e8e2026\u5e748\u6708\u516c\u5e03\u3002<\/p>\n<p>\u771f\u6027\u7ea2\u7ec6\u80de\u589e\u591a\u75c7\u662f\u4e00\u79cd\u4ee5\u7ea2\u7ec6\u80de\u8fc7\u5ea6\u751f\u6210\u4e3a\u7279\u5f81\u7684\u7f55\u89c1\u8840\u6db2\u764c\u75c7\u3002\u76ee\u524d\u7684\u6807\u51c6\u6cbb\u7597\u5305\u62ec\u53cd\u590d\u653e\u8840\u548c\u7ec6\u80de\u51cf\u706d\u5242\uff0c\u4f46\u5c1a\u65e0\u4e13\u95e8\u9488\u5bf9\u7ea2\u7ec6\u80de\u548c\u7ea2\u7ec6\u80de\u538b\u79ef\u7684\u83b7\u6279\u7597\u6cd5\u3002Divesiran\u662f\u4e00\u79cd\u9776\u5411TMPRSS6\u7684\u201c\u9996\u521b\u201dsiRNA\u7597\u6cd5\uff0c\u901a\u8fc7\u8c03\u8282\u94c1\u4ee3\u8c22\u6765\u51cf\u5c11\u7ea2\u7ec6\u80de\u7684\u8fc7\u5ea6\u751f\u6210\uff0c\u5df2\u83b7\u5f97<a href=\"https:\/\/www.alphaseek.cn\/?tag=%e7%be%8e%e5%9b%bd\" title=\"View all posts in \u7f8e\u56fd\" target=\"_blank\" class=\"tag_link\">\u7f8e\u56fd<\/a>\u98df\u54c1\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\u9488\u5bf9\u771f\u6027\u7ea2\u7ec6\u80de\u589e\u591a\u75c7\u7684\u5feb\u901f\u901a\u9053\u8d44\u683c\u53ca\u5b64\u513f\u836f\u8d44\u683c\u8ba4\u5b9a\u3002<\/p>\n<p>\u8d23\u4efb\u7f16\u8f91\uff1a\u5f20\u4fca SF065<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Silence Therapeutics\u672c\u5468\u57282026\u5e74\u6b27\u6d32\u8840\u6db2\u5b66\u534f\u4f1a\u5e74\u4f1a\u4e0a\u516c\u5e03\u4e86\u5176\u5728\u7814siRNA\u7597\u6cd5dive 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